Study Finds GRAS Carcinogenicity Data are Adequate, but Could Use a Standardized Approach

A recent review of carcinogenicity data submitted to support U.S. FDA “Generally Recognized as Safe” (GRAS) determinations for food substances has shown that, although the types of carcinogenicity data are varied, safety is typically adequately evidenced. Still, a standardized approach defining which data is required to support a GRAS determination could be useful.